Saturday 25 July 2009

Unoprostone




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

S01EE02

CAS registry number (Chemical Abstracts Service)

0120373-36-6

Chemical Formula

C22-H38-O5

Molecular Weight

382

Therapeutic Category

Glaucoma treatment

Chemical Names

(+)-(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid (WHO)

(+)-Isopropyl Z-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoate

Foreign Names

  • Unoprostonum (Latin)
  • Unoproston (German)
  • Unoprostone (French)
  • Unoprostona (Spanish)

Generic Names

  • Synthetic analogue of dinoprost (IS: prostaglandin F2alpha)
  • Isopropyl unoprostone (OS: JAN)
  • UF 021 (IS)

Brand Names

  • Rescula
    Astellas, Taiwan; Novartis, Argentina; Novartis, Brazil; Novartis, Chile; Novartis, Czech Republic; Novartis, Mexico; Novartis, Philippines; Novartis, Thailand; Novartis, Venezuela; Novartis Ophthalmics, Colombia; Novartis Ophthalmics, Colombia; Novartis Ophthalmics, Hungary; Novartis Ophthalmics, Peru; Santen, Japan

International Drug Name Search

Glossary

ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday 22 July 2009

Valbazen




In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Valbazen



Albendazole

Albendazole is reported as an ingredient of Valbazen in the following countries:


  • Australia

  • Austria

  • Belgium

  • France

  • Germany

  • Ireland

  • Italy

  • Luxembourg

  • Netherlands

  • Norway

  • South Africa

  • Sweden

  • Switzerland

  • United Kingdom

  • United States

International Drug Name Search

Saturday 18 July 2009

Dry-Clox





Dosage Form: FOR ANIMAL USE ONLY
Dry-Clox®

(cloxacillin benzathine)

Intramammary Infusion

FOR USE IN DRY COW ONLY

NADA 055-058



Caution:


Federal law restricts this drug to use by or on the order of a licensed veterinarian.



Description:


Dry-Clox (cloxacillin benzathine) for Intramammary Infusion into the Dry Cow is a product which provides bactericidal activity against gram-positive bacteria. The active agent, cloxacillin benzathine, is a sparingly soluble salt of the semisynthetic penicillin, cloxacillin. Cloxacillin is a derivative of 6-aminopenicillanic acid, and therefore is chemically related to other penicillins. It has, however, the antibacterial properties described below, which distinguish it from certain other penicillins.


Each 10 mL disposable syringe contains cloxacillin benzathine equivalent to 500 mg of cloxacillin activity in a stable peanut oil gel. This product was manufactured by a non-sterilizing process.



Storage:


Do not store above 25°C (77°F). Do not freeze.



Action:


In the non-lactating mammary gland, Dry-Clox (cloxacillin benzathine) provides bactericidal levels of the active antibiotic, cloxacillin, for a prolonged period of time. This prolonged activity is due to the low solubility of the cloxacillin benzathine and to the slow-release oil-gel base. This prolonged contact between the antibiotic and the pathogenic organism enhances the probability of a bacteriological cure.


Cloxacillin is not destroyed by the enzyme, penicillinase, and therefore, is active against penicillin-resistant strains of Staphylococcus aureus. It is also active against non-penicillinase-producing Staphylococcus aureus as well as Streptococcus agalactiae.


The class disc, Methicillin 5 mcg, should be used to estimate the in vitro susceptibility of bacteria to cloxacillin.



Indications:


For the treatment of mastitis in dairy cows during the dry period.


Dry-Clox has been shown by extensive clinical studies to be efficacious in the treatment of mastitis in dry cows, when caused by Streptococcus agalactiae and Staphylococcus aureus including penicillin-resistant strains.


Treatment of the dry cow with Dry-Clox is indicated in any cow known to harbor any of these organisms in the udder at drying off, or which has had repeated attacks of mastitis during the previous lactation, or is affected with mastitis at drying off, if caused by susceptible organisms.



Dosage for Dry Cows:


Infuse the contents of one syringe (10 mL) into each infected quarter following the last milking or early in the dry period. See Directions for Use.



Directions for Use:


Dry-Clox (cloxacillin benzathine) is for use in dry cows only. Administer immediately after the last milking, or early in the dry period. Use no later than 30 days prior to calving.


Completely milk out all four quarters. The udder and teats should be thoroughly washed with warm water containing a suitable dairy antiseptic and dried, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry.


Dry-Clox is packaged with the Opti-Sert® Protective Cap.


For partial insertion: Twist off upper portion of the Opti-Sert Protective Cap to expose 3–4 mm of the syringe tip.


For full insertion: Remove protective cap to expose the full length of the syringe tip.


Insert syringe tip into the teat canal and expel the entire contents of syringe into the quarter. Withdraw the syringe and gently massage the quarter to distribute the medication.


Do not infuse contents of the mastitis syringe into the teat canal if the Opti-Sert Protective Cap is broken or damaged.



Precautions:


Because it is a derivative of 6-aminopenicillanic acid, Dry-Clox has the potential for producing allergic reactions. Such reactions are rare; however, should they occur, the subject should be treated with antihistamines or pressor amines, such as epinephrine.



Residue Warnings:


1. For use in dry cows only.


2. Not to be used within 30 days of calving.


3. Any animal infused with this product must not be slaughtered


for food until 30 days after the latest infusion.



How Supplied


Dry-Clox (cloxacillin benzathine) Intramammary Infusion is supplied as 10 mL syringes containing 500 mg of cloxacillin activity per syringe. One display carton contains 12 syringes.


NDC 0010-4720-01 - 10 mL syringe



Opti-Sert is a registered trademark of Wyeth LLC - used under license.


Dry-Clox is a registered trademark of Boehringer Ingelheim Vetmedica, Inc.


© 2010 Boehringer Ingelheim Vetmedica, Inc. All Rights Reserved.


12110 4300J



Syringe Label




Carton










Dry-Clox 
cloxacillin benzathine  liquid










Product Information
Product TypePRESCRIPTION ANIMAL DRUGNDC Product Code (Source)0010-4720
Route of AdministrationINTRAMAMMARYDEA Schedule    








Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
CLOXACILLIN BENZATHINE (CLOXACILLIN)CLOXACILLIN500 mg  in 10 mL





Inactive Ingredients
Ingredient NameStrength
No Inactive Ingredients Found


















Product Characteristics
Color    Score    
ShapeSize
FlavorImprint Code
Contains      














Packaging
#NDCPackage DescriptionMultilevel Packaging
10010-4720-0112 SYRINGE In 1 CARTONcontains a SYRINGE
110 mL In 1 SYRINGEThis package is contained within the CARTON (0010-4720-01)










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
NADANADA05505803/11/1975


Labeler - Boehringer Ingelheim Vetmedica, Inc (007134091)









Establishment
NameAddressID/FEIOperations
GC Hanford Manufacturing Company002238863MANUFACTURE









Establishment
NameAddressID/FEIOperations
Boehringer Ingelheim Vetmedica, Inc.832511005ANALYSIS









Establishment
NameAddressID/FEIOperations
Boehringer Ingelheim Vetmedica, Inc.832510841ANALYSIS









Establishment
NameAddressID/FEIOperations
ACS Dobfar SPA542848580API MANUFACTURE
Revised: 10/2010Boehringer Ingelheim Vetmedica, Inc



Thursday 16 July 2009

Lentoquine




Lentoquine may be available in the countries listed below.


Ingredient matches for Lentoquine



Hydroquinidine

Hydroquinidine hydrochloride (a derivative of Hydroquinidine) is reported as an ingredient of Lentoquine in the following countries:


  • Spain

International Drug Name Search

Friday 10 July 2009

Rhinocort Hayfever




Rhinocort Hayfever may be available in the countries listed below.


Ingredient matches for Rhinocort Hayfever



Budesonide

Budesonide is reported as an ingredient of Rhinocort Hayfever in the following countries:


  • Australia

International Drug Name Search

Apresia




Apresia may be available in the countries listed below.


Ingredient matches for Apresia



Sertraline

Sertraline is reported as an ingredient of Apresia in the following countries:


  • Poland

International Drug Name Search

Lobiavers




Lobiavers may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Lobiavers



Levamisole

Levamisole hydrochloride (a derivative of Levamisole) is reported as an ingredient of Lobiavers in the following countries:


  • France

International Drug Name Search

Thursday 9 July 2009

Avagard




Ingredient matches for Avagard



Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Avagard in the following countries:


  • Australia

  • United States

International Drug Name Search

Kaliserum Na




Kaliserum Na may be available in the countries listed below.


Ingredient matches for Kaliserum Na



Polystyrene Sulfonic Acid

Polystyrene Sulfonic Acid sodium salt (a derivative of Polystyrene Sulfonic Acid) is reported as an ingredient of Kaliserum Na in the following countries:


  • Japan

International Drug Name Search

Wednesday 8 July 2009

Tilisolol




Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0085136-71-6

Chemical Formula

C17-H24-N2-O3

Molecular Weight

304

Therapeutic Category

ß-Adrenergic blocking agent

Chemical Name

(±)-4-[3-(tert-Butylamino)-2-hydroxypropoxy]-2-methylisocarbostyril

Foreign Names

  • Tilisololum (Latin)
  • Tilisolol (German)
  • Tilisolol (French)
  • Tilisolol (Spanish)

Generic Names

  • Tilisolol Hydrochloride (OS: JAN)
  • N 696 (IS: Nisshin)

Brand Names

  • Selecal
    Taisho Yakuhin, Japan; Toyama Kagaku, Japan

International Drug Name Search

Glossary

ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Docu Soft


Generic Name: docusate (DOK ue sate)

Brand Names: Calcium Stool Softener, Colace, Correctol Softgel Extra Gentle, D-S Caps, Diocto, Doc-Q-Lace, Docu, Docu Soft, Doculase, Docusoft S, DocuSol, DOK, DOS, DSS, Dulcolax Stool Softener, Enemeez Mini, Fleet Sof-Lax, Kao-Tin, Kaopectate Stool Softener, Kasof, Phillips Stool Softener, Silace, Sur-Q-Lax


What is Docu Soft (docusate)?

Docusate is a stool softener. It makes bowel movements softer and easier to pass.


Docusate is used to treat or prevent constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.


Docusate may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Docu Soft (docusate)?


You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist before using docusate if you are on a low-salt diet, if you are pregnant or breast-feeding, or if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.


What should I discuss with my healthcare provider before using Docu Soft (docusate)?


You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist if it is safe for you to take docusate:



  • if you are on a low-salt diet; or




  • if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.




It is not known whether docusate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether docusate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old without the advice of a doctor.

How should I use Docu Soft (docusate)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Take docusate tablets or capsules with a full glass of water. Drink plenty of liquids while you are taking docusate. Do not crush, chew, or break a docusate capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Mix the liquid with 6 to 8 ounces of milk, fruit juice, or infant formula and drink the mixture right away.


Do not take docusate rectal enema by mouth. It is for use only in your rectum. Wash your hands before and after using docusate rectal enema.

Try to empty your bowel and bladder just before using the enema.


Twist off the applicator tip. Lie down on your left side with your knees bent, and gently insert the tip of the enema applicator into the rectum. Squeeze the tube to empty the entire contents into the rectum. Throw away the tube, even if there is still some medicine left in it.


After using docusate, you should have a bowel movement within 12 to 72 hours. Call your doctor if you have not had a bowel movement within 1 to 3 days.


Do not use docusate for longer than 7 days unless your doctor has told you to. Overuse of a stool softener can lead to serious medical problems. Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Since docusate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting or stomach pain.


What should I avoid while using Docu Soft (docusate)?


Avoid using laxatives or other stool softeners unless your doctor has told you to.

Avoid using the bathroom just after using docusate enema.


Docu Soft (docusate) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using docusate and call your doctor at once if you have a serious side effect such as:

  • rectal bleeding or irritation;




  • numbness or a rash around your rectum;




  • severe diarrhea or stomach cramps; or




  • continued constipation.



Less serious side effects may include:



  • mild diarrhea; or




  • mild nausea.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Docu Soft (docusate)?


There may be other drugs that can interact with docusate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Docu Soft resources


  • Docu Soft Side Effects (in more detail)
  • Docu Soft Use in Pregnancy & Breastfeeding
  • Docu Soft Drug Interactions
  • Docu Soft Support Group
  • 0 Reviews for Docu Soft - Add your own review/rating


  • Docusate Professional Patient Advice (Wolters Kluwer)

  • Colace MedFacts Consumer Leaflet (Wolters Kluwer)

  • Diocto Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Docusate Salts Monograph (AHFS DI)

  • Dostinex Monograph (AHFS DI)

  • Enemeez Mini Enema MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Docu Soft with other medications


  • Constipation


Where can I get more information?


  • Your pharmacist can provide more information about docusate.

See also: Docu Soft side effects (in more detail)


Saturday 4 July 2009

Mildronats




Mildronats may be available in the countries listed below.


Ingredient matches for Mildronats



Meldonium

Meldonium is reported as an ingredient of Mildronats in the following countries:


  • Latvia

International Drug Name Search

Thursday 2 July 2009

Lidocaine Sopharma




Lidocaine Sopharma may be available in the countries listed below.


Ingredient matches for Lidocaine Sopharma



Lidocaine

Lidocaine hydrochloride (a derivative of Lidocaine) is reported as an ingredient of Lidocaine Sopharma in the following countries:


  • Bulgaria

International Drug Name Search

Progestérone Biogaran




Progestérone Biogaran may be available in the countries listed below.


Ingredient matches for Progestérone Biogaran



Progesterone

Progesterone is reported as an ingredient of Progestérone Biogaran in the following countries:


  • France

International Drug Name Search